Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment
نویسندگان
چکیده
1 Institute for Infectious Diseases, University of Bern, Bern, Switzerland 6 2 Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland 7 3 Department of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, 8 Bern, Switzerland 9 4 Institute of Biochemistry, Faculty of Medicine, University of Giessen, Giessen, Germany 10 5 Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland 11 6 ZHAW Zurich University of Applied Sciences, School of Life Sciences and Facility Management, 12
منابع مشابه
Polysaccharide Capsule Composition of Pneumococcal Serotype 19A Subtypes Is Unaltered among Subtypes and Independent of the Nutritional Environment.
Serotype 19A strains have emerged as a cause of invasive pneumococcal disease after the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7), and serotype 19A has now been included in the recent 13-valent vaccine (PCV13). Genetic analysis has revealed at least three different capsular serotype 19A subtypes, and nutritional environment-dependent variation of the 19A capsule structu...
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Streptococcus pneumoniae is a major pathogen that causes different invasive pneumococcal diseases (IPD). The pneumococcal polysaccharide capsule is a main virulence factor. More than 94 capsule types have been described, but only a limited number of capsule types accounted for the majority of IPD cases before the introduction of pneumococcal vaccines. After the introduction of the conjugated pn...
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The main virulence factor of Streptococcus pneumoniae is the capsule. The polysaccharides comprising this capsule are encoded by approximately 15 genes and differences in these genes result in different serotypes. The aim of this study was to investigate the sequence diversity of the capsular genes of serotypes 6A, 6B, 6C, 19A and 19F and to explore a possible effect of vaccination on variation...
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تاریخ انتشار 2016